SOP for AMES Test: The AMES test (Bacterial Reverse Mutation test) developed by Bruce Ames in the 1970s, is a widely used method for identifying chemicals that can cause mutations, which in turn can lead to cancer. This test uses different strains of the bacterium Salmonella typhimurium that carry mutations in genes involved in histidine synthesis, allowing them to revert back to being histidine-independent if … Continue reading SOP for AMES Test: Overview in line with OECD Guidelines 471