person holding a petri dish
Genetic

AMES Test Protocol: A Tool for Assessing Genotoxicity

AMES Test Protocol: AMES test, also known as the bacterial reverse mutation test, is a widely used assay for evaluating the mutagenic potential of chemical substances. Developed by Dr. Bruce Ames in the 1970s, this test has become a cornerstone in genetic toxicology and plays a crucial role in the safety assessment of chemicals, drugs, and other substances. The Organization for Economic Cooperation and Development … Continue reading AMES Test Protocol: A Tool for Assessing Genotoxicity

Dr. Anubhav Sharma
Genetic, Science News

SOP for the AMES Test: Overview in line with OECD Guidelines 471

SOP for the AMESTest: The AMES test (Bacterial Reverse Mutation test) developed by Bruce Ames in the 1970s, is a widely used method for identifying chemicals that can cause mutations, which in turn can lead to cancer. This test uses different strains of the bacterium Salmonella typhimurium that carry mutations in genes involved in histidine synthesis, allowing them to revert back to being histidine-independent if … Continue reading SOP for the AMES Test: Overview in line with OECD Guidelines 471

Dr. Anubhav Sharma
man doing a sample test in the laboratory
Science News

MTT Test: Tool in Cytotoxicity Assays and Drug Screening

MTT Test which is a colorimetric assay that plays a critical role in cell proliferation studies and cytotoxicity assays. This technique utilizes a yellow tetrazolium salt, MTT, which is reduced to purple formazan in the mitochondria of living cells. The amount of formazan produced directly correlates with the number of viable cells that enabling scientists to gauge cell viability and cytotoxicity accurately. The MTT Test … Continue reading MTT Test: Tool in Cytotoxicity Assays and Drug Screening

Dr. Anubhav Sharma
person wearing medical gloves holding petri dish
Drug Development

Bacterial Reverse Mutation Test: Test, Procedure, and Analysis

Bacterial Reverse Mutation test also popularly known as the Ames test which plays a pivotal role in understanding genetic mutations. AMES Test has the ability to assess the potential mutagenic properties of various compounds. With the integration of this test into our scientific practices, we have taken significant strides in genotoxicity testing, pharmaceutical research and even environmental analysis. The Origin of the Bacterial Reverse Mutation … Continue reading Bacterial Reverse Mutation Test: Test, Procedure, and Analysis

Dr. Anubhav Sharma
Mysteries of Poisonous Amphibians
Science News

Mysteries of Poisonous Amphibians

Poisonous amphibians have long fascinated scientists and naturalists alike. These creatures, which include poison dart frogs, newts, and salamanders, possess potent toxins in their skin or other glands that serve as a defense mechanism against predators. The mysteries surrounding these creatures encompass various aspects, such as their toxin production, their immunity to their own toxins, and their use of coloration as a warning signal to … Continue reading Mysteries of Poisonous Amphibians

Dr. Anubhav Sharma
a person holding a spinosaurus dinosaur toy
Science News

Dinosaurs vs Humans: Adapting to a Warmer Planet

Dinosaurs vs Humans: Dinosaurs thrived on a warmer Earth with higher carbon dioxide levels, but the comparison to humans adapting to today’s rapidly changing climate is not a straightforward one. Several key differences between dinosaurs and humans, as well as their respective ecosystems, make it challenging for humans to cope with the consequences of climate change. First, evolutionary timescales play a critical role in how … Continue reading Dinosaurs vs Humans: Adapting to a Warmer Planet

Dr. Anubhav Sharma
New Method to Track Particles in Soft Colloids Using Optical Tweezers
Science News

New Method to Track Particles in Soft Colloids Using Optical Tweezers

Soft Colloids Using Optical Tweezers: Scientists at the Raman Research Institute (RRI) in India have developed a technique to track and manipulate minute clay particle movements within soft clay colloids using optical tweezers. This innovative method could have applications in areas such as targeted drug delivery. The researchers used optical tweezers to study the dynamics and hidden structural details of Laponite, a synthetic clay commonly … Continue reading New Method to Track Particles in Soft Colloids Using Optical Tweezers

Dr. Anubhav Sharma
India-Israel Friendship: Research and Development Cooperation Begins
Science News

India-Israel Friendship: Research and Development Cooperation Begins

India-Israel Friendship: In a significant milestone for Science and Technology cooperation between India and Israel, the Council of Scientific and Industrial Research (CSIR) under India’s Ministry of Science and Technology (MoST) and the Directorate of Defense Research and Development (DDR&D) under Israel’s Ministry of Defense have signed a Memorandum of Understanding (MoU) on Industrial Research and Development Cooperation. Dr. N Kalaiselvi, DG of CSIR and … Continue reading India-Israel Friendship: Research and Development Cooperation Begins

Dr. Anubhav Sharma
Tips to Manage Acid Reflux During Pregnancy
Science News

Tips to Manage Acid Reflux During Pregnancy

Acid Reflux During Pregnancy- Acid reflux or heartburn is a prevalent pregnancy-related symptom, affecting up to 45% of gestating women. However, there are a variety of strategies that can help manage acid reflux. No matter your trimester of pregnancy or what symptoms are manifesting themselves at any given moment – there’s always something you can do to alleviate them! What is Acid Reflux During Pregnancy? … Continue reading Tips to Manage Acid Reflux During Pregnancy

Dr. Anubhav Sharma
Regular Eye Exams can Detect 10 Life-Threatening Diseases
Science News

Regular Eye Exams can Detect 10 Life-Threatening Diseases

Regular Eye Exams are essential in maintaining good eye health and early disease detection – which could prevent vision loss and even save lives. While not every disease shows obvious symptoms, regular exams can reveal early warning signs that could save lives in some instances. Here we list 10 life-threatening diseases which regular exams could detect. Regular Eye Exams can Detect 10 Life-Threatening Diseases Diabetes … Continue reading Regular Eye Exams can Detect 10 Life-Threatening Diseases

Dr. Anubhav Sharma
Plant Authentication: A Guide to Herbal Research- Pharmacognosy
Pharma News, Pharmacognosy

Plant Authentication: A Guide to Herbal Research- Pharmacognosy

Plant Authentication- Learn about the importance of plant authentication in herbal research and the various methods used to authenticate plants, including macroscopic characteristics, microscopic characteristics, chromatographic techniques, and DNA analysis. Get a comprehensive guide to plant authentication in pharmacognosy. Introduction Herbal medicine relies on accurate identification of plant species to assess therapeutic properties and potential side effects, making authentication such an integral component of herbal … Continue reading Plant Authentication: A Guide to Herbal Research- Pharmacognosy

Dr. Anubhav Sharma
Cesarean Delivery May Increase the Risk of Colorectal Cancer
Science News

Cesarean Delivery May Increase the Risk of Colorectal Cancer

Cesarean Delivery: Women often have the option to opt for cesarean delivery if medical complications make vaginal birth unsafe, such as too large of an infant for your birth canal or slow cervical thinning. Increased Risk of Early-Onset CRC Early-onset colorectal cancer (EOCRC) is becoming an ever-increasing global concern. Over the last two decades, its incidence has dramatically risen across many nations including New Zealand … Continue reading Cesarean Delivery May Increase the Risk of Colorectal Cancer

Dr. Anubhav Sharma
bubbles chemistry close up color
Drug Development, Pharma News

Role of Surfactant in Emulsion Stabilization: A Comprehensive Overview

Role of Surfactant in Emulsion: Emulsions are an extremely versatile class of materials with applications in various fields such as food, cosmetics, pharmaceuticals and oil recovery. An emulsion consists of two immiscible liquid phases such as oil and water that mix, with one phase dispersed into droplets within another continuous phase – usually water. Surfactants, surface-active agents are essential in the formation and stabilization of … Continue reading Role of Surfactant in Emulsion Stabilization: A Comprehensive Overview

Dr. Anubhav Sharma
selective focus photography of magazines
Science News

Science News highlights for students: Today’s top stories

Science News highlights for students- Modern life can be fast-paced and ever-evolving, so it is imperative that students keep abreast of current affairs to help them quickly adapt. Every day there are numerous scientific advancements taking place that are both fascinating and alarming. Science News highlights for students 1. Mercury’s Comet-Like Tail Science News highlights for students- Mercury, the innermost planet in our Solar System, … Continue reading Science News highlights for students: Today’s top stories

Dr. Anubhav Sharma
Top Genetic Toxicology News of 2023
Pharma News

Top Genetic Toxicology News of 2023

Genetic Toxicology News of 2023- Genetic Toxicology Testing Market is set to see tremendous growth due to increased government and academic spending on proteomics, genomics research, drug design development in India and North America as well as increasing demand for humanized animal models. 1. Personalized Medicine Genetic Toxicology News of 2023- Personalized medicine is the next frontier of healthcare, combining genomics and big data analytics … Continue reading Top Genetic Toxicology News of 2023

Dr. Anubhav Sharma